Determining oncogenic patterns and cancer predisposition through the transcriptomic profile in Mitchell–Riley syndrome with heterotopic gastric mucosa and duodenal atresia: a case report

Table 1. DEGs interactors of RFX6 in our analysis

Gene symbol	Gene name	Control mean counts	MRS mean counts	Fold change	q-value
AGAP4	ArfGAP with GTPase domain, ankyrin repeat and PH domain 4	97.37	4969.96	5.67	6.96e−24
ATR	ATR serine/threonine kinase	1005.56	5420.26	2.43	4.94e−12
EHBP1	EH domain binding protein 1	316.07	2251.49	2.84	1.93e−20
EIF2AK3	Eukaryotic translation initiation factor 2 alpha kinase 3	761.30	4152.75	2.45	6.13e−14
GHRL	Ghrelin and obestatin prepropeptide	308.44	16.68	− 4.21	1.58e−02
GLIS3	GLIS family zinc finger 3	13.28	200.13	3.88	2.23e−04
GPR68	G protein-coupled receptor 68	806.28	0	− 8.04	6.51e−04
IER3IP1	Immediate early response 3 interacting protein 1	303.11	0	− 6.63	5.38e−03
IFT88	Intraflagellar transport 88	192.00	1250.83	2.70	4.18e−11
MAFB	MAF bZIP transcription factor B	1639.27	216.81	− 2.92	3.19e−03
PLAGL1	PLAG1 like zinc finger 1	963.13	166.78	− 2.53	1.11e−04
RFX7	Regulatory factor X7	794.65	3635.74	2.19	2.45e−07
RPGRIP1L	RPGRIP1 like	55.03	300.20	2.42	2.47e−04
SYTL4	Synaptotagmin like 4	24.76	200.13	3.01	6.69e−03

We highlighted the transcripts mean counts obtained after DESeq2 normalization, the fold changes computed as log₂ (MRS mean counts/control mean counts) and the q-value for each of the DEGs in our analysis that interacts with RFX6 in STRING. All values are rounded to the second decimal digit

ISSN: 1750-1172