The role of estrogen deprivation therapy in premenopausal women with primary unresectable intracardiac leiomyomatosis: a systematic review and meta-analysis

Table 1 Demographic, clinical and treatment factors of 114 reviewed cases of intracardiac leiomyomatosis

Item	Case
Item	Number	Percent (%)
Total number of cases	114
Median age in years (range)	46.5 (24–72)
Publication Year	114
Within last 10 years	72	63.16
Earlier than 10 years ago	42	36.84
Presenting symptoms ¹	102
Gynecological symptoms	15	14.71
Cardiopulmonary symptoms	56	54.90
Both gynecological and cardiopulmonary symptoms	12	11.76
Without symptoms	19	18.63
Menopausal status	114
Premenopausal or younger than 50 years old	85	74.56
Postmenopausal or older than 50 years old	29	25.44
Pathological features	114
Benign leiomyoma	107	93.86
Atypical histologic features	3	2.63
Unknown	4	3.51
Treatment	114
Incomplete excision	37	32.46
Complete excision	73	64.04
Unknown	2	1.75
Died perioperatively ²	2	1.75
Admitted by which departments¹	94
Department of Cardio-Thoracic Surgery	58	61.70
Department of Obstetrics and Gynaecology	32	34.04
Other Departments ³	4	4.26
Records with BSO or Ovarian Preservation¹	79
Admitted by Department of Obstetrics and Gynaecology	30
With BSO	28	93.33
Ovarian Preservation	2	6.67
Admitted by Department of Cardio-Thoracic Surgery or other Departments	49
With BSO	32	65.31
Ovarian Preservation	17	34.69
Status of Adhesion at the level of IVC or above (ALIA), Status of pulmonary nodules (PN)	114
Firm/extensive ALIA, and/or PN	27	23.68
No/slight ALIA, no PN	61	53.51
Unknown	26	21.81

The significance of bold highlight the number of cases in each group or subgroup
¹available data less than 114; ²one died preoperatively, one died postoperatively; ³three were admitted by Emergency Department and one were admitted by Department of Gastrointestinal Surgery

ISSN: 1750-1172