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Fig. 3 | Orphanet Journal of Rare Diseases

Fig. 3

From: Considerations on diagnosis and surveillance measures of PTEN hamartoma tumor syndrome: clinical and genetic study in a series of Spanish patients

Fig. 3

mRNA expression analyses. Relative mRNA expression of KLLN (A), PTEN (B) and PTENP1 (C), determined by qPCR using 36B4 as a reference gene. Control individuals were compared to subgroups of PHTS patients according to the variant status of PTEN. Only significant differences are indicated (two tailed t-test; *p < 0.05; **p < 0.01; ***p < 0.001; **** p < 0.0001). Each dot represents the mean value of the expression of the gene under study for each patient (assessed in triplicate). The mean value of each group ± SEM is indicated

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Orphanet Journal of Rare Diseases

ISSN: 1750-1172