Table 3 Predictors of each quality of life trajectory (SF-36) across baseline, 3–5 year and 7–13 year follow-ups
Predictor variable | Physical Component Summary (SF-36) | Mental Component Summary (SF-36) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
β | S.E | p | 95%CI Lower Bound | 95%CI Upper Bound | β | S.E | p | 95%CI Lower Bound | 95%CI Upper Bound | |
Intercept | 32.21 | 2.35 | .001* | 26.83 | 36.11 | 47.57 | 2.32 | .001* | 42.82 | 51.94 |
Time of assessment | − 0.05 | 0.24 | .852 | − 0.51 | 0.46 | − 0.08 | 0.24 | .775 | − 0.51 | 0.40 |
Male sex | − 5.24 | 2.34 | .027* | − 8.64 | 0.73 | − 0.07 | 0.22 | .731 | − 5.95 | 4.80 |
Younger age at diagnosis | 0.25 | 0.06 | .001* | 0.13 | 0.37 | 0.03 | 0.07 | .544 | − 0.10 | 0.17 |
Cardiac ejection fraction (EF ≤ 50%) | 3.14 | 2.53 | .148 | − 1.66 | 8.19 | − 6.85 | 2.74 | .003* | − 11.89 | − 0.95 |
Small fibre neuropathy | 11.66 | 2.29 | .001* | 6.59 | 15.51 | 5.24 | 3.01 | .031* | − 0.74 | 11.17 |
Higher GFR (ml/min) | 0.21 | 0.04 | .001* | 0.12 | 0.28 | 0.03 | 0.04 | .326 | − 0.06 | 0.12 |
History of cerebrovascular events | 5.12 | 1.99 | .003* | 1.65 | 9.34 | 4.51 | 1.96 | .004* | 0.70 | 8.16 |
− 2LL without interaction | 636.9 | 642.9 | ||||||||
Time*Significant predictors | ||||||||||
Time*Gender | 0.25 | 0.76 | .771 | − 1.46 | 1.62 | – | – | – | – | – |
Time*Age | − 0.01 | 0.03 | .655 | − 0.06 | 0.05 | – | – | – | – | – |
Time*Cardiac EF ≤ 50% | – | – | – | – | – | − 0.21 | 0.80 | .796 | − 1.45 | 1.76 |
Time*Small fibre neuropathy | 0.43 | 0.69 | .560 | − 1.04 | 1.64 | − 0.05 | 0.80 | .943 | − 2.00 | 1.28 |
Time*Measured GFR (ml/min) | − 0.01 | 0.01 | .404 | − 0.03 | 0.01 | – | – | – | – | – |
Time*History of cerebrovascular event | − 0.30 | 0.76 | .713 | − 1.78 | 1.21 | 0.67 | 0.63 | .916 | − 1.47 | 1.05 |
− 2LL with interaction | 631.7 | 642.7 | ||||||||