Table 2 This table shows the supplementation with calcium and vitamin D (analogues and metabolites) and biochemical exams during three trimesters of the pregnancy in women with HypoPT and with Pseudo-HypoPT
HypoPT women | |||||||||
|---|---|---|---|---|---|---|---|---|---|
I° trimester | II° trimester | III° trimester | |||||||
Medications | N | Mean ± SD | Range | N | Mean ± SD | Range | N | Mean ± SD | Range |
Calcium carbonate, mg/day | 25 | 1600 ± 1050 | 500–4000 | 25 | 1795 ± 1265.6 | 250–6000 | 25 | 1802 ± 1242 | 500–6000 |
Calcitriol, µg/day | 25 | 0.8 ± 0.4 | 0–2 | 25 | 1 ± 0.7 | 0–3 | 25 | 0.94 ± 0.62 | 0–3 |
Cholecalciferol, IU/day | 10 | 1059.7 ± 522.4 | 400–2000 | 8 | 1389.6 ± 1063.6 | 400–3666.7 | 8 | 1121 ± 653 | 400–2000 |
Other biochemical examsa | |||||||||
|---|---|---|---|---|---|---|---|---|---|
Phosphate serum, mg/dl [2.5–4.9] | 15 | 4.3 ± 1.2 | 1.1–6.3 | 17 | 4.2 ± 1.2 | 1.3–5.8 | 15 | 4.3 ± 1.1 | 1.8–5.8 |
Urinary calcium, mg/24 h [100–300] | 5 | 231.9 ± 119 | 69–350 | 5 | 301 ± 224.4 | 166–698 | 5 | 379 ± 168 | 260–570 |
Creatinine, mg/dl [0.5–1.3] | 15 | 0.7 ± 0.1 | 0.5–0.9 | 9 | 0.6 ± 0.1 | 0.4–0.8 | 12 | 0.7 ± 0.1 | 0.5–0.8 |
Creatinine Clearance, ml/min [> 60] | 7 | 104.9 ± 19.3 | 75–123 | 5 | 110.6 ± 16.1 | 90–127 | 5 | 97.4 ± 13 | 90–120 |
25 (OH) vitamin D, ng/ml [30–100] | 9 | 31.9 ± 10.3 | 13–44 | 7 | 38.5 ± 19.9 | 15–79.7 | 4 | 21.5 ± 13.3 | 7–36.1 |
Magnesium, mg/dl [1.5–2.6] | 8 | 1.7 ± 0.4 | 0.7–2 | 5 | 1.5 ± 0.4 | 0.7–1.9 | 3 | 1.9 ± 0.1 | 1.8– 1.9 |
Pseudo-HypoPT women | |||||||||
|---|---|---|---|---|---|---|---|---|---|
I° trimester | II° trimester | III° trimester | |||||||
Medications | N | Mean ± SD | Range | N | Mean ± SD | Range | N | Mean ± SD | Range |
Calcium carbonate, mg/day | 3 | 875 ± 530 | 500–1250 | 3 | 875 ± 530 | 500–1250 | 3 | 1125 ± 177 | 1000–1250 |
Calcitriol, µg/day | 3 | 0.7 ± 10 | 50–80 | 3 | 0.7 ± 10 | 50–80 | 3 | 0.8 ± 29 | 50–100 |
Cholecalciferol, IU/day | 2 | 2466 ± 1225 | 1600–1333 | 2 | 2466 ± 1225 | 1600–3333 | 2 | 2466 ± 1225 | 1600–3333 |
Other biochemical examsa | |||||||||
|---|---|---|---|---|---|---|---|---|---|
Albumin-corrected calcium, mg/dl [8.5–10.1] | 3 | 9.3 ± 0.8 | 8.7–9.8 | 3 | 9.2 ± 0.2 | 9–9.4 | 3 | 9.1 ± 0.7 | 8.6–9.6 |
Phosphate serum, mg/dl [2.5–4.9] | 2 | 4.1 ± 0.4 | 3.8–4.4 | 3 | 4.0 ± 0.7 | 3.5–4.8 | 3 | 3.9 ± 0.1 | 3.8–4 |
Urinary calcium, mg/24 h [100–300] | 1 | 86 ± 0 | 86–86 | 1 | 215 ± 0 | 215–215 | 1 | 156 ± 0 | 156–156 |
Creatinine, mg/dl [0.5–1.3] | 2 | 0.7 ± 0.1 | 0.6–0.7 | 2 | 0.6 ± 0 | 0.6–0.6 | 2 | 0.5 ± 0 | 0.5–0.5 |