Executive functions and quality of life in children with neurofibromatosis type 1

Table 3 Results of executive function assessment for children with NF1 and healthy controls

Executive function assessment	Children with NF1			Healthy controls			t(df)^e	p value^e	Cohen’s d
Executive function assessment	n	Mean	(SD)	n	Mean	(SD)	t(df)^e	p value^e	Cohen’s d
Performance-based tests
ROCF, planning index^a	39	4.49	4.11	56	1.20	3.11	4.231 (66.96)	< 0.001	0.904
Stroop, time interference^a	40	129.40	57.35	56	95.75	45.81	3.076 (72.04)	0.003	0.648
Stroop, errors^a	40	4.28	4.92	56	1.41	2.02	3.483 (48.44)	0.001	0.763
WMI^b	39	83.23	12.98	56	100.48	14.42	6.086 (87.01)	< 0.001	1.257
MCST, categories^a	40	3.95	1.52	56	4.11	1.34	0.524 (77.63)	0.602	0.110
MCST, perseverations^a	40	4.40	3.71	56	4.05	3.00	0.488 (72.74)	0.627	0.103
T2B, speed^a	38	104.50	32.26	55	119.80	32.53	2.241 (80.15)	0.028	0.472
T2B, accuracy^a	38	8.16	6.40	55	4.23	4.03	3.351 (57.17)	0.001	0.734
Auditory attention^c	35	8.86	2.10	55	10.46	1.18	4.101 (47.87)	< 0.001	0.936
Behavioral inventories
BRIEF-parent, GEC^d	40	63.35	15.05	53	46.75	9.81	6.068 (63.13)	< 0.001	1.306
BRIEF-parent, BRI_d	40	61.45	16.76	53	47.30	9.69	4.770 (58.38)	< 0.001	1.033
BRIEF-parent, MI_d	40	62.80	13.11	53	46.85	9.31	6.548 (67.07)	< 0.001	1.403
BRIEF-teacher, GEC_d	34	64.29	13.30	45	47.89	14.02	5.303 (73.07)	< 0.001	1.201
BRIEF-teacher, BRI_d	34	61.21	17.31	45	46.04	6.34	4.866 (39.73)	< 0.001	1.163
BRIEF-teacher, MI_d	34	65.21	13.03	45	46.93	7.34	7.344 (48.64)	< 0.001	1.728

ROCF = Rey–Osterrieth complex figure; WMI = working memory index; MCST = modified card sorting test; T2B = two barrages test; BRIEF = behavior rating inventory of executive function; GEC = global executive composite; BRI = behavioral regulation index; MI = metacognition index
^aRaw score
^bStandardized score (M = 100, SD = 15)
^cStandardized scale score (M = 10, SD = 3)
^dStandardized T score (M = 50, SD = 10)
^eAll values shown correspond to the degrees of freedom, t and p corrected (Welch correction)

ISSN: 1750-1172