Long-term effectiveness of carglumic acid in patients with propionic acidemia (PA) and methylmalonic acidemia (MMA): a randomized clinical trial

Table 2 Poisson regression analysis of the rate of ER visits (intention-to-treat population)

	Rate ratio	95% LCL	95% UCL	P-value
Treatment
*Carglumic acid versus standard therapy	0.4945	0.2904	0.8422	0.0095
Treatment
**Carglumic acid versus standard therapy	0.4991	0.3017	0.8256	0.0068
Gender
Male versus female	0.5834	0.2864	1.1884	0.1377
Disease type
MMA versus PA	0.8340	0.4416	1.5752	0.576
Age in years	0.9959	0.9845	1.0073	0.4795

*Poisson model including treatment only as an independent variable
**Poisson model including treatment, gender, disease type, and age as an independent variable

ISSN: 1750-1172