Table 1 Summary statistics in 1637 patients
Characteristic | mRS 0–2 (n = 1544) | mRS 3 + (n = 93) | Overall (n = 1637) |
|---|---|---|---|
Age at enrollment | 48 (32.5–59) | 56 (43–64) | 49 (33–60) |
Female | 921 (60%) | 52 (56%) | 973 (59%) |
Mutation | |||
 ACVRL1 | 457/1081 (42%) | 18/52 (35%) | 475/1133 (42%) |
 Endoglin | 588/1081 (54%) | 31/52 (60%) | 619/1133 (55%) |
 SMAD4 | 35/1081 (3%) | 3/52 (6%) | 38/1133 (3%) |
Brain VM | 314/1537 (20%) | 28/92 (30%) | 342/1629 (21%) |
Pulmonary AVM | 737/1488 (50%) | 51/90 (57%) | 788/1578 (50%) |
Liver VM | 239/1469 (16%) | 28/91 (31%) | 267/1560 (17%) |
GI bleeding | 230/1483 (16%) | 34/91 (39%) | 264/1571 (17%) |
Anemia | 688/1490 (46%) | 63/88 (72%) | 751/1578 (48%) |