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Table 5 Clinical features of 14 IgG4-related thyroiditis

From: Clinical features and treatment efficacy for IgG4-related thyroiditis

Sex/age Disease duration (m) Symptoms Affected organs Diagnosis Serum IgG4 (mg/L) Thyroid US Baseline RI Treatment
F/52 108 Goiter, hardened thyroid, lymph node swelling, abdominal pain, arthralgia LN, thyroid Possible 7100 Diffuse thyroid enlargement 4 GCs 30 mg qd
LS
F/56 120 Goiter, hardened thyroid, lower limb edema, chills Kidney, pituitary, sinus, thyroid Definite 5300 Diffuse thyroid enlargement 10 GCs 40 mg qd
MMF 0.75 g bid
LS
M/26 3 Goiter, hardened thyroid, neck compression Pancreas, thyroid Definite 11,400 Diffuse thyroid enlargement 4 GCs 50 mg qd
LS
F/54 120 Goiter, hardened thyroid, neck compression, lymph node swelling LN, thyroid Definite 2600 Diffuse thyroid enlargement 4 GCs 40 mg qd
LS
M/58 6 Goiter, hardened thyroid, neck compression Thyroid, liver, LN Definite 3130 Diffuse thyroid enlargement 6 GCs 40 mg qd
LS
F/52 7 Goiter, hardened thyroid, neck compression, dyspnea Thyroid Possible 2210 Diffuse thyroid enlargement with nodular changes of the left lobe 4 Iguratimod 25 mg bid
M/31 36 Goiter, hardened thyroid Thyroid Definite 1850 Goiter with low-level echo in the middle of the left lobe 2 LS
M/36 5 Goiter, hardened thyroid, fatigue Thyroid Possible 3250 Diffuse thyroid enlargement 2 GCs 40 mg qd
LS
F/16 48 Goiter, hardened thyroid Thyroid Possible 5130 Diffuse thyroid enlargement 2 LS
F/59 24 Goiter, hardened thyroid, neck compression, lower limb edema Thyroid Definite 4370 Diffuse thyroid enlargement, calcification within the right lobe 2 Iguratimod 25 mg bid
LS
M/29 96 Goiter, hardened thyroid Thyroid Possible 16,000 Diffuse thyroid enlargement 2 Iguratimod 25 mg bid
M/61 96 Goiter, hardened thyroid, LG enlargement SMG, LG, lung, LN, thyroid Possible 20,600 Diffuse thyroid enlargement with solid nodules within the left lobe 10 GCs 30 mg qd
CTX 100 mg qd
LS
M/41 8 Goiter, hardened thyroid, nausea and vomiting PAO, pachymeningitis, sinus, thyroid Possible 1548 Diffuse thyroid enlargement 10 GCs 60 mg qd
CTX 100 mg qd
TMX 10 mg bid
LS
F/28 6 Goiter, hardened thyroid Thyroid Possible 7540 Diffuse thyroid enlargement
Multiple flaky hypoechoic areas
2 LS
  1. Normal range of serum IgG4: 80-1400 mg/L
  2. US: ultrasound; Baseline RI represented baseline IgG4-RD responder index; LN: lymph nodes; SMG: submandibular gland; LG: lacrimal gland; PAO: periaortitis; GCs: glucocorticoids. CTX: Cyclophosphamide. MMF: Mycophenolate Mofetil. TMX: tamoxifen. LS: levothyroxin sodium