Table 2 Baseline symptoms and organs affected of IgG4-RD patients with/without thyroiditis
From: Clinical features and treatment efficacy for IgG4-related thyroiditis
Symptoms and organs affected at baseline | IgG4-related thyroiditis (n = 14) | IgG4-RD without thyroiditis (n = 42) | P value |
|---|---|---|---|
Symptoms at baseline (n, %) | |||
Goiter | 14 (100.0) | 0 (0) | < 0.001* |
Hardened thyroid | 14 (100.0) | 0 (0) | < 0.001* |
Neck compression | 5 (35.7) | 0 (0) | 0.001* |
Lower limb edema | 2 (14.3) | 2 (4.8) | 0.258 |
Lymph node swelling | 2 (14.3) | 9 (21.4) | 0.711 |
Lacrimal gland enlargement | 1 (7.1) | 17 (40.5) | 0.023* |
Abdominal pain | 1 (7.1) | 10 (23.8) | 0.258 |
Arthralgia | 1 (7.1) | 3 (7.1) | 1.000 |
Cough | 1 (7.1) | 7 (16.7) | 0.664 |
Nausea and vomiting | 1 (7.1) | 5 (11.9) | 1.000 |
Chills | 1 (7.1) | 0 (0) | 0.250 |
Dyspnea | 1 (7.1) | 0 (0) | 0.250 |
Fatigue | 1 (7.1) | 0 (0) | 0.250 |
Submandibular gland enlargement | 0 (0) | 14 (33.3) | 0.012* |
Jaundice | 0 (0) | 5 (11.9) | 0.316 |
Parotid gland enlargement | 0 (0) | 3 (7.1) | 0.565 |
Nasal congestion | 0 (0) | 7 (16.7) | 0.174 |
Organs affected (n, %) | |||
Lymph node | 4 (28.6) | 18 (42.9) | 0.267 |
Pancreas | 1 (7.1) | 19 (45.2) | 0.011* |
Submandibular gland | 1 (7.1) | 17 (40.5) | 0.019* |
Lacrimal gland | 1 (7.1) | 16 (38.1) | 0.022* |
Lung | 1 (7.1) | 16 (38.1) | 0.021* |
Kidney | 1 (7.1) | 6 (14.2) | 0.657 |
Bile duct | 0 (0) | 11 (26.2) | 0.025* |
Parotid gland | 0 (0) | 5 (11.9) | 0.307 |
Nasal sinus | 2 (14.3) | 11 (26.2) | 0.480 |
Prostate | 0 (0) | 6 (22.2) | 0.306 |
Pituitary | 2 (14.3) | 1 (2.4) | 0.151 |
Periaortitis/periarteritis | 1 (7.1) | 2 (4.8) | 1.000 |
Pachymeningitis | 1 (7.1) | 0 (0) | 0.250 |
Liver | 1 (7.1) | 1 (2.4) | 0.441 |