|
Characteristics at diagnosis
|
Dercum (n = 9)
|
LMS (n = 11)
|
Lean controls (n = 18)
|
p DD versus Lean
|
p LMS versus Lean
|
p DD versus LMS
|
|---|
|
History
| | | | | | |
|
Dysimmune disorders (%; n/N)
|
22% (2/9)
|
45% (5/11)
|
0% (18/18)
|
–
|
–
|
–
|
|
Paraclinical
| | | | | | |
|
Hemoglobin (g/dL)
|
14.3 [12.5–15.4]
|
14.6 [12–15.4]
|
15 [12.1–17.3]
|
0.07
|
0.41
|
0.46
|
|
Platelets (103/mm3)
|
266 [211–310]
|
220 [104–255]
|
210 [176–338]
|
0.005
|
0.39
|
0.10
|
|
Leukocytes (103/mm3)
|
7.8 [5–9.1]
|
5.8 [5.2–9.8]
|
5.4 [4.3–11.1]
|
0.02
|
0.49
|
0.19
|
|
CRP (mg/L)
|
3 [3–18]
|
3 [3–10]
|
3 [3, 4]
|
0.11
|
0.65
|
0.52
|
|
Leukocyte differential: (/mm3)
| | | | | | |
|
Lymphocytes
|
1939 [1100–2000]
|
1832 [600–2300]
|
1950 [1600–3300]
|
> 0.9
|
0.72
|
0.63
|
|
Monocytes
|
500 [500–700]
|
400 [400–600]
|
400 [300–900]
|
0.21
|
> 0.9
|
0.33
|
|
Nuclear neutrophils
|
5200 [2600–10000]
|
3300 [2500–4600]
|
2800[1200–3260]
|
0.50
|
0.35
|
0.14
|
|
Eosinophils
|
150 [0–300]
|
100 [0–500]
|
100 [0–1600]
|
> 0.9
|
0.26
|
0.20
|
|
Basophils
|
52 [30–100]
|
19 [0–37]
|
0 [0–14]
|
0.001
|
0.57
|
0.001
|
|
Lymphocytes subpopulations (n/N)
|
(5/9)
|
(7/11)
|
(18/18)
| | | |
|
CD3+
|
1420 [1105–1904]
|
867 [513–1584]
|
1444[913–2607]
|
> 0.9
|
0.009
|
0.04
|
|
CD4+
|
1255 [790–1710]
|
636.5 [328–922]
|
866 [367–1653]
|
0.23
|
0.048
|
0.03
|
|
CD8+
|
479 [454–788]
|
227[140–310]
|
546 [284–943]
|
> 0.9
|
0.014
|
0.007
|
|
B Lymphocytes
|
204.5 [140–760]
|
227 [101–310]
|
211 [103–528]
|
> 0.9
|
> 0.9
|
0.93
|
|
NK Lymphocytes
|
207.5 [40–225]
|
210 [124–300]
|
292 [136–450]
|
0.049
|
0.31
|
0.53
|
- The number of patients studied was indicated only when at least one data point was missing: n: number of examinations performed/ N: total number of patients in the group
- *: p < 0.05, **: p < 0.01, ***: p < 0.001, ns: non significant; p > 0.05*: p < 0.05, **: p < 0.01, ***: p < 0.001, ns: non significant
