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Table 3 Main immunohematological characteristics of Dercum’s disease (DD) and Roch-Leri lipomatosis (LMS) groups compared to the lean control group

From: Metabolic and immunological phenotype of rare lipomatoses: Dercum’s disease and Roch-Leri mesosomatic lipomatosis

Characteristics at diagnosis Dercum (n = 9) LMS (n = 11) Lean controls (n = 18) p DD versus Lean p LMS versus Lean p DD versus LMS
History       
Dysimmune disorders (%; n/N) 22% (2/9) 45% (5/11) 0% (18/18)
Paraclinical       
Hemoglobin (g/dL) 14.3 [12.5–15.4] 14.6 [12–15.4] 15 [12.1–17.3] 0.07 0.41 0.46
Platelets (103/mm3) 266 [211–310] 220 [104–255] 210 [176–338] 0.005 0.39 0.10
Leukocytes (103/mm3) 7.8 [5–9.1] 5.8 [5.2–9.8] 5.4 [4.3–11.1] 0.02 0.49 0.19
CRP (mg/L) 3 [3–18] 3 [3–10] 3 [3, 4] 0.11 0.65 0.52
Leukocyte differential: (/mm3)       
Lymphocytes 1939 [1100–2000] 1832 [600–2300] 1950 [1600–3300]  > 0.9 0.72 0.63
Monocytes 500 [500–700] 400 [400–600] 400 [300–900] 0.21  > 0.9 0.33
Nuclear neutrophils 5200 [2600–10000] 3300 [2500–4600] 2800[1200–3260] 0.50 0.35 0.14
Eosinophils 150 [0–300] 100 [0–500] 100 [0–1600]  > 0.9 0.26 0.20
Basophils 52 [30–100] 19 [0–37] 0 [0–14] 0.001 0.57 0.001
Lymphocytes subpopulations (n/N) (5/9) (7/11) (18/18)    
CD3+ 1420 [1105–1904] 867 [513–1584] 1444[913–2607]  > 0.9 0.009 0.04
CD4+ 1255 [790–1710] 636.5 [328–922] 866 [367–1653] 0.23 0.048 0.03
CD8+ 479 [454–788] 227[140–310] 546 [284–943]  > 0.9 0.014 0.007
B Lymphocytes 204.5 [140–760] 227 [101–310] 211 [103–528]  > 0.9  > 0.9 0.93
NK Lymphocytes 207.5 [40–225] 210 [124–300] 292 [136–450] 0.049 0.31 0.53
  1. The number of patients studied was indicated only when at least one data point was missing: n: number of examinations performed/ N: total number of patients in the group
  2. *: p < 0.05, **: p < 0.01, ***: p < 0.001, ns: non significant; p > 0.05*: p < 0.05, **: p < 0.01, ***: p < 0.001, ns: non significant