Table 1 Main phenotypic characteristics of patients belonging to the Dercum’s disease and Roch Leri lipomatosis (LMS) groups
Characteristics at diagnosis | Dercum (n = 9) | LMS (n = 11) | p |
|---|---|---|---|
Clinical data | |||
Sex-ratio (M/F) | 0.5 (3 M/6F) | 1.75 (7 M/4F) | 0.005 |
Age (years) | 30.8 [16–50] | 31.2 [18–68] | 0.69 |
Weight (kg) | 89 [58–98] | 100 [55–142] | 0.42 |
BMI (kg/m2) | 32 [27–59] | 31 [25–35] | 0.71 |
Number of lipomas > 10 (%; n/N) | 89% (8/9) | 82% (9/11) | > 0.9 |
Encapsulated—fibrotic—ecchymotic (%; n/N) | 89–11–11% (9/9) | 100–9–9% (11/11) | > 0.9 |
History of surgery (%; n/N) | 56% (7/9) | 54.5% (6/11) | > 0.9 |
Lipomas sites | |||
Forearm/arm (%; n/N) | 56% (5/9) | 82% (9/11) | 0.042 |
Back | 56% (5/9) | 27% (3/11) | 0.87 |
Abdomen | 44% (4/9) | 55% (6/11) | 0.99 |
Thigh | 67% (6/7) | 73% (8/11) | > 0.99 |
Flank/ Lumbar fossa | 44% (4/9) | 36% (4/11) | > 0.99 |
Legs | 11% (1/9) | 27% (3/11) | 0.80 |
Other | 44% (4/9) | 9% (1/11) | 0.048 |
Personal history | |||
Treated hypertension (%; n/N) | 22% (2/9) | 64% (7/11) | 0.33 |
Diabetes (%; n/N) | 33% (3/9) | 9% (1/11) | 0.28 |
Treated dyslipidemia (%; n/N) | 11% (1/9) | 45% (5/11) | 0.16 |
Family history | |||
History of lipomatosis | 11% (1/9) | 27% (3/11) | > 0.9 |
History of diabetes | 55% (5/9) | 9% (1/11) | > 0.9 |