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Table 1 Main phenotypic characteristics of patients belonging to the Dercum’s disease and Roch Leri lipomatosis (LMS) groups

From: Metabolic and immunological phenotype of rare lipomatoses: Dercum’s disease and Roch-Leri mesosomatic lipomatosis

Characteristics at diagnosis Dercum (n = 9) LMS (n = 11) p
Clinical data
Sex-ratio (M/F) 0.5 (3 M/6F) 1.75 (7 M/4F) 0.005
Age (years) 30.8 [16–50] 31.2 [18–68] 0.69
Weight (kg) 89 [58–98] 100 [55–142] 0.42
BMI (kg/m2) 32 [27–59] 31 [25–35] 0.71
Number of lipomas > 10 (%; n/N) 89% (8/9) 82% (9/11)  > 0.9
Encapsulated—fibrotic—ecchymotic (%; n/N) 89–11–11% (9/9) 100–9–9% (11/11)  > 0.9
History of surgery (%; n/N) 56% (7/9) 54.5% (6/11)  > 0.9
Lipomas sites
Forearm/arm (%; n/N) 56% (5/9) 82% (9/11) 0.042
Back 56% (5/9) 27% (3/11) 0.87
Abdomen 44% (4/9) 55% (6/11) 0.99
Thigh 67% (6/7) 73% (8/11)  > 0.99
Flank/ Lumbar fossa 44% (4/9) 36% (4/11)  > 0.99
Legs 11% (1/9) 27% (3/11) 0.80
Other 44% (4/9) 9% (1/11) 0.048
Personal history
Treated hypertension (%; n/N) 22% (2/9) 64% (7/11) 0.33
Diabetes (%; n/N) 33% (3/9) 9% (1/11) 0.28
Treated dyslipidemia (%; n/N) 11% (1/9) 45% (5/11) 0.16
Family history
History of lipomatosis 11% (1/9) 27% (3/11)  > 0.9
History of diabetes 55% (5/9) 9% (1/11)  > 0.9
  1. The number of patients studied was indicated only when at least one data point was missing: n: number of examinations performed/ N: total number of patients in the group
  2. *: p < 0.05, **: p < 0.01, ***: p < 0.001, ns: non significant; p > 0.05*: p < 0.05, **: p < 0.01, ***: p < 0.001, ns: non significant