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Table 7 Comparison of mutations versus cystic structure

From: Non-hotspot PIK3CA mutations are more frequent in CLOVES than in common or combined lymphatic malformations

Cystic structure

Mutation

Hotspot

Non-hotspot

No mutation

Input data

    

Microcystic

48

43

5

14

Macrocystic

21

21

0

13

Mixed

28

26

2

4

Unknown

11

2

9

4

group_1

group_2

p value

Adjusted p value

 

Fisher's exact test Mutation/no mutation

    

Microcystic

Macrocystic

0.1536

0.2304

 

Microcystic

Mixed

0.2815

0.2815

 

Macrocystic

Mixed

0.0241

0.0722

 

group_1

group_2

p value

Adjusted p value

 

Fisher's exact test Hotspot/non-hotspot

    

Microcystic

Macrocystic

0.3132

0.7500

 

Microcystic

Mixed

1.0000

1.0000

 

Macrocystic

Mixed

0.5000

0.7500

 
  1. Kruskal-Wallis chi-squared = 5.906, df = 3, p value = 0.1163
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Orphanet Journal of Rare Diseases

ISSN: 1750-1172