Table 1 Estimates of birth incidence for RCDP and carriers per gene and population
Gene | US | EU5 (UK, Germany, France, Italy and Spain) | ||||
|---|---|---|---|---|---|---|
Births | 95% confidence range | Carriers (in thousands) | Births | 95% confidence range | Carriers (in thousands) | |
PEX7 | 11.8 | (9.3–14.6) | 1130 | 14.2 | (11.4–17.4) | 1395 |
GNPAT | 5.0 | (3.7–6.4) | 732 | 7.4 | (5.7–9.4) | 1006 |
AGPS | 0.3 | (0.1–0.4) | 168 | 0.5 | (0.3–0.8) | 269 |
FAR1 | 0.6 | (0.3–0.9) | 246 | 0.1 | (0.0–0.2) | 126 |
PEX5 (PTS2 domain) | 0.3 | (0.2–0.5) | 189 | 0.4 | (0.2–0.6) | 228 |
Total | 18 | (14–23) | 2465 | 23 | (18–28) | 3024 |