From: Clinical, genetic and quality-of-life study of a cohort of adult patients with tuberous sclerosis
Standardized physical component Mean (SD) | Standardized mental component Mean (SD) | p-value | |
---|---|---|---|
Seizures | |||
No (N = 17) | 50.11 (8.79) | 47.59 (7.14) | PC:0.054 |
Yes, controlled, no seizures in 1 year (N = 23) | 48.38 (8.29) | 44.12 (8.16) | |
Yes, controlled, seizures in last year (N = 4) | 42.83 (10.16) | 50.05 (7.91) | MC:0.264 |
Uncontrolled (N = 5) | 37.52 (14.61) | 42.15 (9.23) | |
TAND | |||
No (N = 26) | 49.39 (8.55) | 47.21(6.47) | PC: 0.002 |
Mild (N = 13) | 50.75 (6.44) | 42.49 (10.31) | |
Moderate (N = 5) | 41.96 (8.64) | 49.94 (4.56) | MC: 0.104 |
Severe (N = 5) | 33.98 (13.33) | 41.08 (8.17) | |
Cortical dysplasia | |||
No (N = 6) | 50.85 (6.92) | 47.40 (6.21) | PC: 0.211 |
Yes (N = 43) | 46.94 (10.13) | 45.36(8.24) | MC: 0.378 |
No (N = 22) | 46.86 (9.76) | 44.09 (8.43) | PC: 0.994 |
Subependymal nodule | |||
Yes (N = 27) | 47.88 (10.04) | 46.85 (7.54) | MC: 0.628 |
Astrocytoma | |||
No (N = 34) | 48.73 (8.04) | 45.44 (8.71) | PC: 0.008 |
Yes (N = 15) | 44.46 (12.84) | 45.99 (6.32) | MC: 0.198 |
AML | |||
None (N = 16) | 50.41(7.60) | 47.37 (7.57) | PC: 0.461 |
Single (N = 2) | 49.12 (7.72) | 46.48 (5.41) | |
Several (N = 5) | 46.16 (4.33) | 47.74 (6.66) | MC: 0.555 |
Multiple > 3 (N = 26) | 47.42 (11.62) | 44.05 (8.63) | |
LAM | |||
No (N = 34) | 47.74 (10.02) | 45.58 (7.64) | PC: 0.851 |
Mild (N = 10) | 48.08 (9.47) | 47.09 (4.96) | |
Moderate (N = 4) | 44.77 (11.96) | 46.59 (13.84) | MC: 0.145 |
Severe (N = 1) | 40.76 | 27.81 | |
Skin | |||
No (N = 8) | 52.61 (7.73) | 48.62 (6.52) | PC: 0.297 |
Yes (N = 41) | 46.41 (9.95) | 45.02 (8.18) | MC: 0.536 |
Rhabdomyoma | |||
No (N = 33) | 48.00 (9.90) | 45.91 (7.53) | PC: 0.739 |
Yes ( N = 16) | 46.24 (9.87) | 45.00 (9.09) | MC: 0.208 |
Retinal hamartoma | |||
No (N = 40) | 46.99 (10.39) | 45.16 (8.63) | PC: 0.241 |
Yes (N = 9) | 49.36 (6.89) | 47.61 (3.81) | MC: 0.023 |
Diagnosis | |||
Childhood (N = 27) | 47.2 (10.1) | 43.46 (9.04) | PC: 0.519 |
Adult (N = 20) | 48.04 (9.55) | 48.25 (5.47) | MC:0.023 |