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Table 3 Analysis of plasma amino acid plasma levels and dietary practices (natural protein and special amino acid mixture intake) according to ferritin levels using multilevel linear regression

From: Severe anemia in patients with Propionic acidemia is associated with branched-chain amino acid imbalance

 

Regression coefficient (95% CI)

p value

Natural protein intake (g/kg/day)

− 72.1 (− 119.6; − 24.5)

0.003

Special mixture of precursor-free amino acids intake (g/kg/day)

37.8 (6.1; 69.5)

0.019

Valine (µmol/L)

− 8.6 (− 12.3; − 4.8)

< 0.001

Isoleucine (µmol/L)

− 5.2 (− 12; 1.5)

0.128

Leucine (µmol/L)

5.6 (2.2; 9.1)

0.001

Valine/Leucine

− 771.5 (− 987.4; − 555.5)

< 0.001

Isoleucine/Leucine

− 431 (− 788.6; − 73.3)

0.018