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Table 3 Proportion of individuals with interstitial lung disease and reticulonodular density determined by high resolution computed tomography

From: Prospective study of the natural history of chronic acid sphingomyelinase deficiency in children and adults: eleven years of observation

Parameter

Baseline visit

Year 1 visit

Final visit

(N = 59)

(N = 50)

(N = 32)

Interstitial lung disease

 

n (%)

 

Absent

14 (23.7)

11 (22.0)

3 (9.4)

Present

39 (66.1)

31 (62.0)

25 (78.1)

 Mild

10 (16.9)

5 (10.0)

6 (18.8)

 Moderate

4 (6.8)

7 (14.0) left; 6 (12.0) right

3 (9.4)

 Severe

25 (42.4)

19 (38.0) left; 20 (40.0) right

16 (50.0)

Reticulonodular density

 

n (%)

 

Absent

14 (23.7)

11 (22.0)

3 (9.4)

Present

39 (66.1)

31 (62.0)

25 (78.1)

 Mild

10 (16.9)

5 (10.0)

6 (18.8)

 Moderate

4 (6.8)

7(14.0) left; 6 (12.0) right

5 (15.6)

 Severe

25 (42.4)

19(38.0) left; 20 (40.0) right

14 (43.8)

  1. All values were the same in both lungs except where values for both the right and left lungs are provided