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Table 3 Proportion of individuals with interstitial lung disease and reticulonodular density determined by high resolution computed tomography

From: Prospective study of the natural history of chronic acid sphingomyelinase deficiency in children and adults: eleven years of observation

Parameter Baseline visit Year 1 visit Final visit
(N = 59) (N = 50) (N = 32)
Interstitial lung disease   n (%)  
Absent 14 (23.7) 11 (22.0) 3 (9.4)
Present 39 (66.1) 31 (62.0) 25 (78.1)
 Mild 10 (16.9) 5 (10.0) 6 (18.8)
 Moderate 4 (6.8) 7 (14.0) left; 6 (12.0) right 3 (9.4)
 Severe 25 (42.4) 19 (38.0) left; 20 (40.0) right 16 (50.0)
Reticulonodular density   n (%)  
Absent 14 (23.7) 11 (22.0) 3 (9.4)
Present 39 (66.1) 31 (62.0) 25 (78.1)
 Mild 10 (16.9) 5 (10.0) 6 (18.8)
 Moderate 4 (6.8) 7(14.0) left; 6 (12.0) right 5 (15.6)
 Severe 25 (42.4) 19(38.0) left; 20 (40.0) right 14 (43.8)
  1. All values were the same in both lungs except where values for both the right and left lungs are provided