Skip to main content

Table 1 Common cell processes defective in LSDs that may be impacted by CB1/CB2 modulator drugs

From: New paradigms for the treatment of lysosomal storage diseases: targeting the endocannabinoid system as a therapeutic strategy

Cell function

Reference example

Autophagy

[39]

Calcium homeostasis

[40]

Cell survival/death

[41]

Endo/exocytosis (vesicular transport)

[42]

Endothelial cell function (BBB integrity)

[43]

Extracellular matrix production/fibrosis

[44]

Inflammation

[21]

Mitochondrial function/energy balance

[45]

Myelination

[46]

Synaptic function

[47]

Back to article page

Orphanet Journal of Rare Diseases

ISSN: 1750-1172