Pregnancy after the diagnosis of lymphangioleiomyomatosis (LAM)

Table 1 Baseline characteristics of patients with lymphangioleiomyomatosis

Characteristics	Numbers (%)
Patients	30
Age of diagnosis (years)	29.4 ± 4.9
Diagnosis
TSC-LAM	3 (10.0)
Sporadic-LAM	27 (90.0)
Complications
Renal AML	11 (36.7)
History of pneumothorax	14 (56.7)
History of chylothorax	7 (23.3)
Pulmonary function testing^a
FEV₁ (L)	2.17 ± 0.77
FEV₁/pred (%)	73.78 ± 25.66
FVC (L)	3.19 ± 0.57
FVC/pred (%)	93.70 ± 16.58
FEV₁/FVC (%)	66.80 ± 19.19
DLco (mmol/min/kPa)	5.27 ± 2.29
DLco pred (%)	48.31 ± 21.13
6-min walking distance (m)^b	509.43 ± 68.90
Total score on St. George’s Respiratory Questionnaire^c	32.91 ± 19.17
History of pregnancy before diagnosis of LAM	18 (60.0)
Patients with live birth	16 (53.3)
Patients with spontaneous abortion	0
Patients with pneumothorax during pregnancy	2 (6.7)

Data with a normal distribution are presented as the means ± standard deviation (SD), and data with a nonnormal distribution are reported as the median (Q1, Q3)
AML angiomyolipoma, DLco diffusing capacity for carbon monoxide, FEV₁ forced expiratory volume in 1 s, FVC forced vital capacity, LAM lymphangioleiomyomatosis, TSC tuberous sclerosis complex
^aSample size for pulmonary function testing was 21
^bSample size for 6-min walking testing was 21
^cSample size for St. George’s respiratory questionnaire was 22

ISSN: 1750-1172