SMA3 | Number of patients with three copies of SMN2 | Mean age of onset in patients with three copies of SMN2 | Number of patients with four copies of SMN2 | Mean age of onset in patients with four copies of SMN2 | p value |
---|---|---|---|---|---|
All | 133 | 3.01 years (SD 3.3; 1 month–18 years) | 99 | 6.71 years (SD 5.86; 1 month–20 years) | < 0.0001 |
Female | 72 | 2.35 years (SD 1.9; 1 month–12 years) | 30 | 5.13 years (SD 4.46; 1 month–16 years) | < 0.0001 |
Male | 61 | 3.78 years (SD 4.3; 0.5–18 years) | 69 | 7.1 years (SD 5.85 years; 1 month–20 years) | < 0.0001 |