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Table 3 The values of echocardiographic parameters of left ventricular chamber dimensions and function of the 48 patients with MPS II

From: Natural progression of cardiac features and long-term effects of enzyme replacement therapy in Taiwanese patients with mucopolysaccharidosis II

Echocardiographic parameters

LVMI (z score)

RVDd (z score)

IVSd (z score)

IVSs (z score)

LVIDd (z score)

LVIDs

(z score)

LVPWd (z score)

LVPWs (z score)

AoD (z score)

LAD (z score)

Mean (SD)

1.05 (2.05)

0.60 (1.33)

2.66 (2.04)

1.06 (1.36)

0.44 (2.35)

0.23 (2.44)

0.86 (1.73)

0.68 (1.53)

1.97 (1.41)

− 0.56 (1.46)

r value (z score versus age)

0.300

0.211

0.325

0.420

− 0.084

− 0.267

0.379

0.314

0.228

0.172

p value

p < 0.05

p > 0.05

p < 0.05

p < 0.01

p > 0.05

p > 0.05

p < 0.01

p > 0.05

p > 0.05

p > 0.05

z score > 2, n (%)

15 (31%)

5 (12%)

26 (54%)

12 (25%)

8 (17%)

7 (15%)

6 (13%)

10 (21%)

22 (46%)

2 (4%)

  1. MPS, mucopolysaccharidosis; LVMI, left ventricular mass index; RVDd, right ventricular end diastolic dimension; IVSd, interventricular septum thickness in diastole; IVSs, interventricular septum thickness in systole; LVIDd, left ventricular internal diameter in diastole; LVIDs, left ventricular internal diameter in systole; LVPWd, left ventricular posterior wall thickness in diastole; LVPWs, left ventricular posterior wall thickness in systole; AoD, aortic diameter; LAD: left atrial dimension; SD, standard deviation