Table 2 Demographic and medical characteristics
From: Impact of pediatric hypophosphatasia on behavioral health and quality of life
Participant demographics | Untreated patients (n = 15) | Patients treated with asfotase alfa (n = 15) |
|---|---|---|
Mean (SD) | Mean (SD) | |
Age of child (Years) | 7.2 (3.3) | 8.7 (4.1) |
N (%) | N (%) | |
|---|---|---|
Gender (% Male) | 8 (53%) | 8 (53%) |
Medical history | ||
Premature loss of deciduous teeth | 10 (67%) | 15 (100%) |
Bowing of long bones in arms or legs | 1 (7%) | 8 (53%) |
Recurrent bone fractures | 1 (7%) | 2 (13%) |
Poorly healing bone fractures | 0 | 1 (7%) |
Short stature | 4 (27%) | 7 (47%) |
Muscle problems (e.g., muscle weakness, gait problems) | 4 (27%) | 12 (80%) |
Craniosynostosis | 0 | 5 (33%) |
Chiari malformation | 0 | 3 (20%) |
Seizures | 0 | 2 (13%) |
Chronic headaches | 3 (20%) | 8 (53%) |
Fatigue | 3 (20%) | 11 (73%) |