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Table 4 Initial parameters associated with death using a Cox regression model

From: Initial predictors for short-term prognosis in anti-melanoma differentiation-associated protein-5 positive patients

  Univariate analysis Multivariate analysis
HR 95% CI P value HR 95% CI P value
Age ≥ 55 years 5.0 2.1–11.9  < 0.001*
Disease duration < 2 months 2.1 0.9–5.2 0.088
Lymphocyte < 0.6 × 109/L 2.5 1.0–6.4 0.047*
Serum ferritin ≥ 2000 ng/ml 14.9 5.2–42.6  < 0.001*
KL-6 ≥ 1600 U/ml 23.6 7.2–77.2  < 0.001* 3.7 1.5–9.1 0.004*
CRP ≥ 5.8 mg/L 5.1 2.2–11.9  < 0.001* 3.7 1.0–12.8 0.044*
ESR ≥ 23 mm/h 3.6 1.4–9.1 0.006*
Anti-Ro52 2.9 1.2–7.4 0.021*
Total CT GGO score ≥ 4 10.8 4.4–26.4  < 0.001* 4.8 1.3–17.9 0.020*
Total CT fibrosis score ≥ 10 49.7 11.4–216.1  < 0.001*
Initial combined treatment 0.1 0.04–0.3  < 0.001* 0.3 0.1–0.8 0.019*
  1. KL-6, Krebs von den Lungen-6; CRP, C-reactive protein; ESR, erythrocyte sedimentation rate; GGO, ground-glass opacity
  2. *Significant