Table 4 Initial parameters associated with death using a Cox regression model
| Â | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
HR | 95% CI | P value | HR | 95% CI | P value | |
Age ≥ 55 years | 5.0 | 2.1–11.9 |  < 0.001* | – | – | – |
Disease duration < 2 months | 2.1 | 0.9–5.2 | 0.088 | – | – | – |
Lymphocyte < 0.6 × 109/L | 2.5 | 1.0–6.4 | 0.047* | – | – | – |
Serum ferritin ≥ 2000 ng/ml | 14.9 | 5.2–42.6 |  < 0.001* | – | – | – |
KL-6 ≥ 1600 U/ml | 23.6 | 7.2–77.2 |  < 0.001* | 3.7 | 1.5–9.1 | 0.004* |
CRP ≥ 5.8 mg/L | 5.1 | 2.2–11.9 |  < 0.001* | 3.7 | 1.0–12.8 | 0.044* |
ESR ≥ 23 mm/h | 3.6 | 1.4–9.1 | 0.006* | – | – | – |
Anti-Ro52 | 2.9 | 1.2–7.4 | 0.021* | – | – | – |
Total CT GGO score ≥ 4 | 10.8 | 4.4–26.4 |  < 0.001* | 4.8 | 1.3–17.9 | 0.020* |
Total CT fibrosis score ≥ 10 | 49.7 | 11.4–216.1 |  < 0.001* | – | – | – |
Initial combined treatment | 0.1 | 0.04–0.3 |  < 0.001* | 0.3 | 0.1–0.8 | 0.019* |