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Table 1 Clinical features of conventional and fibrosarcomatous DFSP

From: Clinicopathological features of fibrosarcomatous dermatofibrosarcoma protuberans and the construction of a back-propagation neural network recognition model

Variables C-DFSP FS-DFSP Total P value
n = 195 n = 26 n = 221
Age at presentation (y)     
 Mean ± SD 30.7 ± 14.4 35.4 ± 12.7 31.24 ± 14.23 0.091
 Median (range) 30.0 (0–66.0) 36.5 (12–57.0) 30.25 (0.0–66.0)  
Age at diagnosis (y)     
 Mean ± SD 37.3 ± 14.5 40.5 ± 10.3 37.69 ± 14.06 0.168
 Median (range) 37.0 (0.3–76.3) 43.1 (20.0–59.0) 37.5 (0.3–76.3)  
The interval of diagnosis (y)     
 Mean ± SD 6.5 ± 6.9 5.1 ± 6.5 6.3 ± 6.9 0.302
 Median (range) 4.3 (0–44.0) 1.8 (0.3–20.7) 4.0 (0–44.0)  
Sex (male/female) 108/87 18/8 126/95 0.18
Size at presentation (cm)     
 Mean ± SD 1.1 ± 1.0 1.0 ± 0.7 1.07 ± 1.05 0.818
 Median (range) 1.0 (0.2–10.0) 1.0 (0.1–3.0) 1.0 (0.1–10.0)  
Size at diagnose     
 Mean ± SD 2.7 ± 2.0 3.1 ± 1.7 2.8 ± 2.0 0.362
 Median (range) 2.0 (0.5–20.0) 3.0 (1.0–8.0) 2.50 (0.5–20.0)  
Tumor growth     
 Mean ± SD 1.7 ± 1.8 2.0 ± 1.7 0.9 ± 0.3 0.337
 Median (range) 1.0 (0–17.0) 1.7 (0–7.0) 1.5 (0–17.0)  
Annual tumor growth     
 Mean ± SD 0.9 ± 2.9 1.8 ± 2.4 0.97 ± 2.84 0.090
 Median (range) 0.3 (0–37.5) 0.7 (0–9.3) 0.3 (0–37.5)  
Location     
 Head-face-neck 21 (10.8%) 5 (19.2%) 26 (11.8%) 0.272
 Shoulder 11(5.6%) 2(7.7%) 13 (5.9%)  
 Chest 51 (26.2%) 8 (30.8%) 59 (26.7%)  
 Abdomen 49 (25.1%) 3 (11.5%) 52 (23.5%)  
 Posterior thighs 40 (20.5%) 8(30.8%) 48 (21.7%)  
 Upper extremity 11 (5.6%) 0 (0) 11 (5.0%)  
 Lower extremity 12 (6.2%) 0 (0) 12 (5.4%)  
Growth type     
 Indolence 29 (14.9%) 1 (3.8%) 30 (13.6%) < 0.001
 Gradually increasing 90 (46.2. %) 4 (15.4%) 94 (42.5%)  
 Rapid enlargement 76 (38.9%) 21 (80.8%) 97 (43.9%)  
Time to rapid enlargement (y)     
 Mean ± SD 5.3 ± 6.5 0.9 ± 1.1 4.4 ± 6.0 0.003
 Median (range) 4.0 (0.1–41.0) 0.6 (0–5.0) 3.0 (0–41.0)  
Cause     
 Trauma 18 0 18 0.140
 Unknown 178 (91.3%) 26(100%) 204 (92.3%)  
Pain 29 2 31  
Metastasis 0 1 1 0.118
Recurrence 4 7 11  
Follow-up     
 Mean ± SD 4.8 ± 2.2 4.9 ± 1.7 4.8 ± 2.1 0.696
 Median (range) 4.6 (1.8–16.6) 4.6 (1.9–8.6) 4.6 (1.8–16.6)  
  1. C-DFSP, conventional dermatofibrosarcoma protuberans; Time to rapid enlargement, time from discovery of the tumor to progressive enlargement of the tumor; FS-DFSP, Dermatofibrosarcoma protuberans with fibrosarcomatous change; y, years