|
Variables
|
C-DFSP
|
FS-DFSP
|
Total
|
P value
|
|---|
|
n = 195
|
n = 26
|
n = 221
|
|---|
|
Age at presentation (y)
| | | | |
|
Mean ± SD
|
30.7 ± 14.4
|
35.4 ± 12.7
|
31.24 ± 14.23
|
0.091
|
|
Median (range)
|
30.0 (0–66.0)
|
36.5 (12–57.0)
|
30.25 (0.0–66.0)
| |
|
Age at diagnosis (y)
| | | | |
|
Mean ± SD
|
37.3 ± 14.5
|
40.5 ± 10.3
|
37.69 ± 14.06
|
0.168
|
|
Median (range)
|
37.0 (0.3–76.3)
|
43.1 (20.0–59.0)
|
37.5 (0.3–76.3)
| |
|
The interval of diagnosis (y)
| | | | |
|
Mean ± SD
|
6.5 ± 6.9
|
5.1 ± 6.5
|
6.3 ± 6.9
|
0.302
|
|
Median (range)
|
4.3 (0–44.0)
|
1.8 (0.3–20.7)
|
4.0 (0–44.0)
| |
|
Sex (male/female)
|
108/87
|
18/8
|
126/95
|
0.18
|
|
Size at presentation (cm)
| | | | |
|
Mean ± SD
|
1.1 ± 1.0
|
1.0 ± 0.7
|
1.07 ± 1.05
|
0.818
|
|
Median (range)
|
1.0 (0.2–10.0)
|
1.0 (0.1–3.0)
|
1.0 (0.1–10.0)
| |
|
Size at diagnose
| | | | |
|
Mean ± SD
|
2.7 ± 2.0
|
3.1 ± 1.7
|
2.8 ± 2.0
|
0.362
|
|
Median (range)
|
2.0 (0.5–20.0)
|
3.0 (1.0–8.0)
|
2.50 (0.5–20.0)
| |
|
Tumor growth
| | | | |
|
Mean ± SD
|
1.7 ± 1.8
|
2.0 ± 1.7
|
0.9 ± 0.3
|
0.337
|
|
Median (range)
|
1.0 (0–17.0)
|
1.7 (0–7.0)
|
1.5 (0–17.0)
| |
|
Annual tumor growth
| | | | |
|
Mean ± SD
|
0.9 ± 2.9
|
1.8 ± 2.4
|
0.97 ± 2.84
|
0.090
|
|
Median (range)
|
0.3 (0–37.5)
|
0.7 (0–9.3)
|
0.3 (0–37.5)
| |
|
Location
| | | | |
|
Head-face-neck
|
21 (10.8%)
|
5 (19.2%)
|
26 (11.8%)
|
0.272
|
|
Shoulder
|
11(5.6%)
|
2(7.7%)
|
13 (5.9%)
| |
|
Chest
|
51 (26.2%)
|
8 (30.8%)
|
59 (26.7%)
| |
|
Abdomen
|
49 (25.1%)
|
3 (11.5%)
|
52 (23.5%)
| |
|
Posterior thighs
|
40 (20.5%)
|
8(30.8%)
|
48 (21.7%)
| |
|
Upper extremity
|
11 (5.6%)
|
0 (0)
|
11 (5.0%)
| |
|
Lower extremity
|
12 (6.2%)
|
0 (0)
|
12 (5.4%)
| |
|
Growth type
| | | | |
|
Indolence
|
29 (14.9%)
|
1 (3.8%)
|
30 (13.6%)
|
< 0.001
|
|
Gradually increasing
|
90 (46.2. %)
|
4 (15.4%)
|
94 (42.5%)
| |
|
Rapid enlargement
|
76 (38.9%)
|
21 (80.8%)
|
97 (43.9%)
| |
|
Time to rapid enlargement (y)
| | | | |
|
Mean ± SD
|
5.3 ± 6.5
|
0.9 ± 1.1
|
4.4 ± 6.0
|
0.003
|
|
Median (range)
|
4.0 (0.1–41.0)
|
0.6 (0–5.0)
|
3.0 (0–41.0)
| |
|
Cause
| | | | |
|
Trauma
|
18
|
0
|
18
|
0.140
|
|
Unknown
|
178 (91.3%)
|
26(100%)
|
204 (92.3%)
| |
|
Pain
|
29
|
2
|
31
| |
|
Metastasis
|
0
|
1
|
1
|
0.118
|
|
Recurrence
|
4
|
7
|
11
| |
|
Follow-up
| | | | |
|
Mean ± SD
|
4.8 ± 2.2
|
4.9 ± 1.7
|
4.8 ± 2.1
|
0.696
|
|
Median (range)
|
4.6 (1.8–16.6)
|
4.6 (1.9–8.6)
|
4.6 (1.8–16.6)
| |
- C-DFSP, conventional dermatofibrosarcoma protuberans; Time to rapid enlargement, time from discovery of the tumor to progressive enlargement of the tumor; FS-DFSP, Dermatofibrosarcoma protuberans with fibrosarcomatous change; y, years
