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Table 1 Demographic and clinical characteristics

From: Experienced complaints, activity limitations and loss of motor capacities in patients with pure hereditary spastic paraplegia: a web-based survey in the Netherlands

 

N = 109

Patient characteristics

n

mean (SD)

Sex (male/female)

54/55

 

Age (years)

 

52.8 (14.2)

Duration of spasticity symptoms (years)

 1–5 years

21

 

 6–10 years

21

 

 11–15 years

16

 

  > 15 years

51

 

 Genetic defect

57

 

 SPG-3a

4

 

 SPG-4

36

 

 SPG-5a

2

 

 SPG-7

3

 

 SPG-8

3

 

 SPG-10

2

 

 SPG-17

1

 

 SPG-31

5

 

 SPG-72

1

 

Positive family history

 First degree relatives

83

 

 Other family members

47

 

 First degree relatives and/or other family members

90

 

 Unknown

8

 

 No

11

 

Non-neurological comorbidities

 Asthma/COPD

6

 

 Diabetes

1

 

 Hypertension

9

 

 Joint disorders*

13

 

 Cardiac problems

4

 

 Other non-neurological comorbidities

7

 
  1. *Rheumatism and osteoarthritis were given as examples to participants. Patients were instructed that this category did not include non-specific back complaints
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Orphanet Journal of Rare Diseases

ISSN: 1750-1172