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Table 1 Demographic and clinical characteristics

From: Experienced complaints, activity limitations and loss of motor capacities in patients with pure hereditary spastic paraplegia: a web-based survey in the Netherlands

  N = 109
Patient characteristics n mean (SD)
Sex (male/female) 54/55  
Age (years)   52.8 (14.2)
Duration of spasticity symptoms (years)
1–5 years 21  
6–10 years 21  
11–15 years 16  
  > 15 years 51  
 Genetic defect 57  
SPG-3a 4  
SPG-4 36  
SPG-5a 2  
SPG-7 3  
SPG-8 3  
SPG-10 2  
SPG-17 1  
SPG-31 5  
SPG-72 1  
Positive family history
First degree relatives 83  
Other family members 47  
First degree relatives and/or other family members 90  
Unknown 8  
No 11  
Non-neurological comorbidities
Asthma/COPD 6  
Diabetes 1  
Hypertension 9  
Joint disorders* 13  
Cardiac problems 4  
Other non-neurological comorbidities 7  
  1. *Rheumatism and osteoarthritis were given as examples to participants. Patients were instructed that this category did not include non-specific back complaints