Treatment of patients with hereditary angioedema with the c.988A>G (p.Lys330Glu) variant in the plasminogen gene

Table 1 Types of hereditary angioedema with normal C1-INH

HAE type	Gene	Nucleotide change	AA change	Chromosome	Variant first described
HAE-FXII	F12	c.983C > A	p.T328K	5	Dewald and Bork 2006 [5]
HAE-FXII	F12	c.983C > G	p.T328R	5	Dewald and Bork 2006 [5]
HAE-FXII	F12	c.971_1018 + 24del72	Indel	5	Bork et al. 2011 [11]
HAE-FXII	F12	c.892_909dup	Duplication p.298_303	5	Kiss et al. 2013 [12]
HAE-PLG	*PLG*	c.988A > G	p.K330E	6	Bork et al 2018 [8]
HAE-ANGPT1	ANGPT1	c.807G > T	p.A119S	8	Bafunno et al. 2018 [7]
HAE-KNG1	KNG1	c.1136 T > A	p.M379K	3	Bork et al. 2019 [9]

AA amino acid, ANGPT1 angiopoietin-1, F12 coagulation factor XII gene, FXII coagulation factor XII protein, HAE hereditary angioedema, HAE-PLG HAE with the c.988A > G (p.K330E) variant in the plasminogen gene; KNG1 kininogen1 gene

ISSN: 1750-1172