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Table 4 Comparisons between mean carotid measures of Morquio A patients treated with Enzyme Replacement Therapy (ERT) and those not treated with ERT

From: Abnormally increased carotid intima media-thickness and elasticity in patients with Morquio A disease

ScoreCovariateDifference (95% CI)P-value
cIMTERT (vs. not)0.00 (−0.03, 0.03)0.916
(mm)Female (vs. Male)−0.01 (−0.05, 0.02)0.402
 Age (per 10 yr)0.01 (− 0.01, 0.02)0.587
 Height (per 10 cm)0.00 (−0.01, 0.00)0.408
cCSDERT (vs. not)−2.20 (−8.91, 4.51)0.520
(%)Female (vs. Male)0.14 (−8.06, 8.34)0.973
 Age (per 10 yr)1.31 (−4.23, 6.86)0.643
 Height (per 10 cm)−2.98 (−5.38, −0.58)0.015
cCSC1ERT (vs. not)−0.03 (− 0.08, 0.02)0.279
(mm2Female (vs. Male)−0.03 (− 0.09, 0.04)0.465
· mm Hg−1)Age (per 10 yr)0.01 (−0.03, 0.05)0.686
 Height (per 10 cm)−0.02 (− 0.04, − 0.01)0.005
cIEMERT (vs. not)136.86 (2.44, 271.29)0.046
(mm Hg)Female (vs. Male)14.88 (− 145.24, 175.00)0.855
 Age (per 10 yr)34.26 (− 105.85, 174.38)0.632
 Height (per 10 cm)130.82 (80.41, 181.23)< 0.001
  1. Analyses are adjusted for sex, age, and height. Significant comparisons are highlighted in bold. Height is a significant influence upon cCSD, cCSC1, and cIEM