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Table 4 Attribute preferences for SMA treatment

From: Treatment preference among patients with spinal muscular atrophy (SMA): a discrete choice experiment

  Coefficient SE 95% CI p value
Level of change in motor function (ref: Stable)      
 Better 0.65 0.09 0.47 0.83 0.000
Change in breathing function (ref: Stable)      
 Better 0.79 0.10 0.60 0.98 0.000
Drug is approved for: (ref: Pediatric and adult patients with SMA)      
 Pediatric patients with SMA under 2 years of age − 1.28 0.10 − 1.47 − 1.09 0.000
Route and frequency of treatments (ref: Intrathecal spinal injection—3–6 times per year)      
 Intravenous injection—one-time treatment 0.51 0.11 0.30 0.73 0.000
 Oral—daily medication 0.80 0.13 0.55 1.04 0.000
Treatments potential risk (ref: Mild risk)      
 Moderate risk − 0.76 0.13 − 1.01 − 0.50 0.000
 Serious, or life-threatening risk − 1.86 0.13 − 2.11 − 1.60 0.000
  1. SE, standard error; CI, confidence interval