Skip to main content

Table 1 The demographic and clinical characteristics of rare cases of bone involvement (n = 64)

From: Unusual sites of bone involvement in Langerhans cell histiocytosis: a systematic review of the literature

Publication decade

N (%)

2000s

17 (28.3)

2010s

43 (71.7)

Region

 

 Asia

30 (46.9)

 Europe

19 (29.7)

 America

12 (18.7)

 Africa

2 (3.1)

 Oceania

1 (1.6)

Gender

 

 Male

45 (70.3)

 Female

19 (29.7)

Age (years)

 

 Less than 1

2 (3.2)

 2–18

29 (45.2)

 19–50

28 (43.8)

 More than 50

5 (7.8)

Category

 

 Unifocal

44 (68.7)

 Multifocal

11 (17.2)

 Multisystem

9 (14.1)

Site of bone involvement

 

 Skull

27 (42.2)

 Facial bonesa

4 (6.2)

 Spine

6 (9.4)

 Chest wallb

15 (23.4)

 Pelvis

6 (9.4)

 Long bones

4 (6.2)

 Short tubular bones

2 (3.1)

Mean age (years)

Mean ± SD (n)

 Children (Age range in children)

7.6 ± 4.3 (n = 31)

 Adults (Age range in adults)

36.4 ± 12 (n = 33)

  1. aMandible, maxilla, nasal bones and orbit
  2. bRib, clavicle, sternum and scapula