Fig. 5From: Clinical disease progression and biomarkers in Niemann–Pick disease type C: a prospective cohort studyBiomarker correlations with disease severity as measured by the 5-domain NPCCSS. a PBMC unesterified cholesterol. b Skin unesterified cholesterol. c Serum cholestane-triol. d PBMC cholesterol esterification. e PBMC HSP70. HSP70: heat shock protein 70; NPCCSS: Niemann–Pick disease type C Clinical Severity Scale; PBMC: peripheral blood mononuclear cellBack to article page