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Table 2 Comparison of intellectual indices between subgroups of CCHS patients using Mask ventilation versus Tracheostomy ventilation

From: Neurocognition in Congenital Central Hypoventilation Syndrome: influence of genotype and ventilation method

 

Mask (n = 16)

Trach (n = 17)

Mean difference

95% CI of the difference

p

Age (years)

8.2 ± 3.7 (n = 16)

9.5 ± 3.4 (n = 17)

− 1.2

− 3.8; − 0.7

0.053

FSIQ

89 ± 17 (n = 16)

70 ± 23 (n = 17)

19

4; 34

0.012*

VCI

95 ± 18 (n = 15)

78 ± 24 (n = 17)

17

2; 33

0.032*

VSI

86 ± 17 (n = 16)

79 ± 24 (n = 17)

7

− 8; 22

0.341

FRI

91 ± 15 (n = 13)

79 ± 25 (n = 17)

11

− 4; 27

0.150

WMI

86 ± 10 (n = 14)

77 ± 15 (n = 16)

9

− 2; 20

0.094

PSI

84 ± 14 (n = 15)

70 ± 17 (n = 16)

14

0.5; 27

0.042*

  1. Data are mean ± SD; n is the number of patients tested
  2. FSIQ full-scale intellectual quotient, VCI verbal comprehension index, VSI visuo-spatial index, FRI fluid reasoning index, WMI working memory index, PSI processing speed index
  3. *p < 0.05 (using ANOVA tests)
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Orphanet Journal of Rare Diseases

ISSN: 1750-1172