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Table 2 Comparison of intellectual indices between subgroups of CCHS patients using Mask ventilation versus Tracheostomy ventilation

From: Neurocognition in Congenital Central Hypoventilation Syndrome: influence of genotype and ventilation method

  Mask (n = 16) Trach (n = 17) Mean difference 95% CI of the difference p
Age (years) 8.2 ± 3.7 (n = 16) 9.5 ± 3.4 (n = 17) − 1.2 − 3.8; − 0.7 0.053
FSIQ 89 ± 17 (n = 16) 70 ± 23 (n = 17) 19 4; 34 0.012*
VCI 95 ± 18 (n = 15) 78 ± 24 (n = 17) 17 2; 33 0.032*
VSI 86 ± 17 (n = 16) 79 ± 24 (n = 17) 7 − 8; 22 0.341
FRI 91 ± 15 (n = 13) 79 ± 25 (n = 17) 11 − 4; 27 0.150
WMI 86 ± 10 (n = 14) 77 ± 15 (n = 16) 9 − 2; 20 0.094
PSI 84 ± 14 (n = 15) 70 ± 17 (n = 16) 14 0.5; 27 0.042*
  1. Data are mean ± SD; n is the number of patients tested
  2. FSIQ full-scale intellectual quotient, VCI verbal comprehension index, VSI visuo-spatial index, FRI fluid reasoning index, WMI working memory index, PSI processing speed index
  3. *p < 0.05 (using ANOVA tests)