Skip to main content

Table 3 Histopathological features of patients with RDD mimic IgG4-RD, RDD or IgG4-RD

From: Rosai–Dorfman disease mimicking IgG4-related diseases: a single-center experience in China

  RDD mimic IgG4-RD (%) RDD (%) RDD total (%) IgG4-RD (%) p valuea
IgG4-Positive Plasma Cells/hpf
 > 100 2/7 (28.6) 0/10 (0.0) 2/17 (11.8) 8/34 (23.5) 0.4632
 > 50 3/7 (42.9) 6/10 (60.0) 9/17 (52.9) 19/34 (55.9) > 0.9999
 10–50(including 50) 2/7 (28.6) 2/10 (20.0) 4/17 (23.5) 7/34 (20.6) > 0.9999
 ≤ 10 0/7 (0.0) 2/10 (20.0) 2/17 (11.8) 0/34 (0.0) 0.1067
IgG4/IgG
 > 40 2/7 (28.6) 5/10 (50.0) 7/17 (41.2) 28/34 (82.4) 0.0045
 10–40(include 40) 4/7 (57.1) 4/10 (40.0) 8/17 (47.1) 6/34 (17.6) 0.0446
 ≤ 10 1/7 (14.3) 1/10 (10.0) 2/17 (11.8) 0/34 (0.0) 0.1067
Specific pathology features
 Storiform fibrosis 0/7 (0.0) 0/10 (0.0) 0/17 (0.0) 17/34 (50.0) 0.0003
 Obliterative phlebitis 0/7 (0.0) 0/10 (0.0) 0/17 (0.0) 2/34 (5.9) 0.5467
 Eosinophilic infiltrate 0/7 (0.0) 0/10 (0.0) 0/17 (0.0) 6/34 (17.6) 0.1612
  1. aMann–Whitney test between RDD total and IgG4-RD. RDD total group includes all the patients in RDD mimic IgG4-RD group and RDD group