Table 3 Histopathological features of patients with RDD mimic IgG4-RD, RDD or IgG4-RD
From: Rosai–Dorfman disease mimicking IgG4-related diseases: a single-center experience in China
RDD mimic IgG4-RD (%) | RDD (%) | RDD total (%) | IgG4-RD (%) | p valuea | |
|---|---|---|---|---|---|
IgG4-Positive Plasma Cells/hpf | |||||
> 100 | 2/7 (28.6) | 0/10 (0.0) | 2/17 (11.8) | 8/34 (23.5) | 0.4632 |
> 50 | 3/7 (42.9) | 6/10 (60.0) | 9/17 (52.9) | 19/34 (55.9) | > 0.9999 |
10–50(including 50) | 2/7 (28.6) | 2/10 (20.0) | 4/17 (23.5) | 7/34 (20.6) | > 0.9999 |
≤ 10 | 0/7 (0.0) | 2/10 (20.0) | 2/17 (11.8) | 0/34 (0.0) | 0.1067 |
IgG4/IgG | |||||
> 40 | 2/7 (28.6) | 5/10 (50.0) | 7/17 (41.2) | 28/34 (82.4) | 0.0045 |
10–40(include 40) | 4/7 (57.1) | 4/10 (40.0) | 8/17 (47.1) | 6/34 (17.6) | 0.0446 |
≤ 10 | 1/7 (14.3) | 1/10 (10.0) | 2/17 (11.8) | 0/34 (0.0) | 0.1067 |
Specific pathology features | |||||
Storiform fibrosis | 0/7 (0.0) | 0/10 (0.0) | 0/17 (0.0) | 17/34 (50.0) | 0.0003 |
Obliterative phlebitis | 0/7 (0.0) | 0/10 (0.0) | 0/17 (0.0) | 2/34 (5.9) | 0.5467 |
Eosinophilic infiltrate | 0/7 (0.0) | 0/10 (0.0) | 0/17 (0.0) | 6/34 (17.6) | 0.1612 |