Table 1 Laboratory data of two patients with VDDR-IA
Ca (mmol/L) | P (mmol/L) | ALP (U/L) | PTH (pg/ml) | 25-(OH)D3 (ng/ml) | 1,25-(OH)2D3 (pg/ml) | |
|---|---|---|---|---|---|---|
Normal range | 2.2–2.8 | 1.00–1.95 | 0–500 | 10–69 | 15–60 | 18.7–47.7 |
Patient 1 | ||||||
Before treatment | 1.36 | 0.89 | 1049 | 235.3 | 79.5 | 9.1 |
After 1 month | 1.91 | 1.38 | ND | 129 | ND | ND |
After 3 months | 2.2 | 1.24 | ND | 246 | ND | ND |
After 4 months | 2.73 | 1.79 | 363 | 59.4 | ND | ND |
After 1 year | 2.63 | 1.95 | ND | 22.7 | 40 | ND |
After 1.7 year | 2.56 | 1.67 | ND | 6.54 | 26.4 | ND |
After 2 years | 2.75 | 1.17 | ND | 3 | 25.2 | ND |
After 2.5 years | 2.64 | 1.4 | ND | 3 | ND | ND |
After 3.3 years | 2.43 | 1.56 | 270 | 12.1 | 34.3 | ND |
After 3.9 years | 2.43 | 1.71 | 333 | 29.6 | 41.6 | ND |
After 4.1 years | 2.53 | 1.41 | 23 | ND | 37.1 | ND |
Patient 2 | ||||||
Before treatment | 1.53 | 0.5 | 4823 | 474 | 149.5 | < 5 |
After 2 months | 2.0 | 0.66 | 1598 | 522 | ND | ND |
After 6 months | 1.94 | 0.83 | 1540 | 311 | 64.37 | ND |
After 1 year | 2.63 | 1.95 | ND | 22.7 | 40 | ND |
After 1.5 year | 2.62 | 1.6 | ND | 19 | ND | ND |
After 2 year | 2.56 | 1.33 | 361 | 14.3 | 28.3 | ND |
After 2.5 year | 2.55 | 1.32 | 525 | ND | 39 | ND |