Table 2 Laboratory findings at diagnosis in clinically-detected and screen-detected patients with type 1 tyrosinemia

Age, months

18

6

2–36

4

1

0–31

0.098

AFP, kU/l

16

148,725

5990–420,800

4

82,868

6470–487,300

0.682

ALT, U/l

17

45

15–111

4

32

10–63

0.362

Calcium, mmol/l

15

2.15

1.26–2.70

4

2.60

2.34–2.60

0.014

Creatinine, μmol/l

14

25

12–103

4

27

24–32

0.327

DBil, μmol/l

12

17

6–38

4

5

3–11

0.013

γ-GT, U/l

14

136

43–328

4

99

91–134

0.327

NH4+ , μmol/l

15

74

36–141

4

65

38–87

0.530

Phosphate, mmol/l

16

0.86

0.22–2.64

4

1.85

0.77–2.19

0.064

PT,  %

16

11

0–37

4

35

15–68

0.029

TBil, μmol/l

17

30

16–48

4

61

14–106

0.144

Tyrosine, μmol/l

16

384

100–840

4

490

452–734

0.099