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Table 1 Clinical characteristics in the three phenotype groups of hepatic involvement

From: Sequence variations of ACVRL1 play a critical role in hepatic vascular malformations in hereditary hemorrhagic telangiectasia

  Group 1 Group 2 Group 3 Total patients p-value
Number of patients 123 138 93 354  
Number of females (% in the group) 55 (55.3%) 84 (60.9%) 67 (72.0%) 206 (58.2%) 4.35 × 10−5
Mean age at hepatic screening ± standard deviation 43.4 ± 15.5 51.5 ± 14.5 57.6 ± 13.0 50.3 ± 15.5 2.5 × 10−11
HHT2 (% of the cohort) 60 (48.8%) 104 (75.4%) 83 (89.2%) 247 (69.8%) 5.85 × 10−11