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Table 1 Clinical characteristics in the three phenotype groups of hepatic involvement

From: Sequence variations of ACVRL1 play a critical role in hepatic vascular malformations in hereditary hemorrhagic telangiectasia

 

Group 1

Group 2

Group 3

Total patients

p-value

Number of patients

123

138

93

354

 

Number of females (% in the group)

55 (55.3%)

84 (60.9%)

67 (72.0%)

206 (58.2%)

4.35 × 10−5

Mean age at hepatic screening ± standard deviation

43.4 ± 15.5

51.5 ± 14.5

57.6 ± 13.0

50.3 ± 15.5

2.5 × 10−11

HHT2 (% of the cohort)

60 (48.8%)

104 (75.4%)

83 (89.2%)

247 (69.8%)

5.85 × 10−11