Table 1 Absolute and relative frequencies of first symptoms which led to diagnostic identification
From: Natural history of Krabbe disease – a nationwide study in Germany using clinical and MRI data
Infantile onset (0 to 12 months) | ||
1. Agitation/Irritability | 24/30 | 80% |
2. Abnormalities in movement pattern and general development regression | 19/30 | 63% |
Onset beyond the first year of life | ||
1. Gait disorder/Abnormalities in movement pattern | 8/8 | 100% |
2. Abnormalities in fine motor skills | 5/8 | 63% |
3. General development regression | 4/8 | 50% |