Skip to main content

Table 3 Results of the TAND Checklist in the TSC cohort

From: The TAND checklist: a useful screening tool in children with tuberous sclerosis and neurofibromatosis type 1

TAND Features NO EPILEPSY(n = 13) (30.9%) Not active EPILEPSY(n = 16) (38.1%) Active EPILEPSY(n = 13) (30.9%) X2 p value
n (%) n (%) n (%)  
Behavioral level
 Anxiety 7 (53.8) 7 (43.8) 5 (38.5) 0.644 0.725
Depressed mood 1 (7.7) 5 (31.3) 0 (0.0) 6.389 0.041
 Extreme shyness 1 (7.7) 5 (31.3) 2 (15.4) 1.592 0.451
 Mood swings 2 (15.4) 5 (31.3) 3 (23.1) 1.001 0.606
 Aggressive outbursts 3 (23.1) 7 (43.8) 7 (53.8) 2.669 0.263
 Temper tantrums 6 (46.2) 10 (62.5) 7 (53.8) 0.780 0.677
 Self-injury 0 (0.0) 3 (18.8) 2 (15.4) 2.622 0.270
Absent or delayed onset of language 2 (15.4) 7 (43.8) 8 (61.5) 5.862 0.050
Repetitive language 0 (0.0) 5 (31.3) 6 (46.2) 7.505 0.023
 Poor eye contact 0 (0.0) 4 (25.0) 4 (30.8) 4.585 0.101
Difficult relationship with peers 0 (0.0) 7 (43.8) 5 (38.5) 7.629 0.022
Repetitive behaviors 2 (15.4) 4 (25.0) 9 (69.2) 9.501 0.009
 Rigidity 4 (30.8) 5 (31.3) 4 (30.8) 0.001 0.999
 Overactivity/hyperactivity 5 (38.5) 6 (37.5) 6 (46.2) 0.255 0.880
 Difficulty paying attention or concentrating 5 (38.5) 12 (75.0) 9 (69.2) 4.489 0.106
 Restlessness 2 (15.4) 4 (25.0) 4 (30.8) 1.001 0.606
 Impulsivity 4 (30.8) 9 (56.3) 10 (76.9) 5.612 0.060
 Difficulties with eating 3 (23.1) 5 (31.3) 5 (31.3) 0.721 0.697
 Sleep difficulties 2 (15.4) 5 (31.3) 6 (46.2) 2.880 0.237
Scholastic level
 Reading 6 (46.2) 6 (37.5) 9 (69.2) 7.008 0.135
 Writing 6 (46.2) 8 (50.0) 9 (69.2) 5.663 0.226
Spelling 2 (15.4) 6 (37.5) 11 (84.6) 13.200 0.001
Mathematics 7 (53.8) 8 (50.0) 11 (84.6) 9.609 0.048
Neuropsychological level
 Memory 3 (23.1) 4 (25.0) 4 (30.8) 0.218 0.897
 Attention 5 (38.5) 11 (68.8) 10 (76.9) 4.591 0.101
Dual-tasking 4 (30.8) 10 (62.5) 10 (76.9) 5.957 0.050
Visuo-spatial tasks 1 (7.7) 1 (6.3) 6 (46.2) 8.981 0.011
Executive skills 3 (23.1) 9 (56.3) 9 (69.2) 5.942 0.050
Getting disoriented 1 (7.7) 4 (25.0) 7 (53.8) 6.946 0.031
Psychosocial level
 Low self-esteem 2 (15.4) 7 (43.8) 2 (15.4) 4.123 0.127
 Very high levels of stress in families 3 (23.1) 8 (50.0) 5 (38.5) 2.206 0.332
 Very high levels of stress between parents 5 (38.5) 8 (50.0) 5 (38.5) 0.538 0.764