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Table 4 Comparison of time to diagnosis in neurological vs non-neurological onset by means of ANCOVA

From: Onset features and time to diagnosis in Friedreich’s Ataxia

  Mean
Time to diagnosis
Standard Error 95% CI p value
All cohort (n = 611)
 Neurological onset (n = 554) 4.5 0.197 4.2–5 0.001
 Non-neurological onset (n = 57) 6.7 0.618 5.5–7.9
Typical-onset patients (n = 508)
 Neurological onset (n = 454) 4.1 0.209 3.7–4.6 0.0002
 Non-neurological onset (n = 56) 6.5 0.594 5.2–7.8
  1. Comparisons were performed both 1) in the entire cohort and 2) in the typical-onset patients. Mean, Standard Error, 95% confidence intervals (CI) and p values estimated by bias-corrected and accelerated bootstrap are reported. Estimates are adjusted for age at examination, age at onset and presentation before/after 1996. Statistically significant results are reported in bold.