Table 1 Definition of the categories neurological and non-neurological onset based on EFACTS registry entries
From: Onset features and time to diagnosis in Friedreich’s Ataxia
Predefined onset symptoms in EFACTS registry | Category Neurological Onset | Category Non-neurological Onset |
|---|---|---|
Instability (yes/no) | At least one of the followings: - Instability - Falls - Others (when a neurological symptom is reported, e.g. clumsinessa) | 1) None of the followings: - Instability - Falls AND 2) Presence of at least one of the followings: - Scoliosis - Cardiomyopathy - Diabetes mellitus - Others (when a non-neurological symptom is reported, e.g. pes cavusb) |
Falls (yes/no) | ||
Scoliosis (yes/no) | ||
Cardiomyopathy (yes/no) | ||
Diabetes Mellitus (yes/no) | ||
Others (yes/no. If yes, symptoms specified in free text) |