Fig. 1
From: Novel MNX1 mutations and genotype–phenotype analysis of patients with Currarino syndrome
Distribution of the nine MNX1 variants detected in CS patients in this study. a Schematic representation of the exon-intron structure of MNX1. Black bars represent exons, and black lines represent introns, with patient variants indicated above the MNX1 genomic structure. b Domain structure of MNX1 (GenBank: NP_005506.3), including the positions (numbers) of identified amino acid alterations. Abbreviation: HOX, homeodomain. Novel and previously reported variants are shown in red and black, respectively, in (a) and (b)