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Table 3 Eye involvement and genetic mutations

From: Ocular lesions in hereditary hemorrhagic telangiectasia: genetics and clinical characteristics

Gene Eye involvement (n = 105) No eye involvement (n = 101) OR (95% CI) p
ACVRL1/ALK1 52 (49.5%) 66 (65.3%) 1 (reference)
ENG 48 (45.7%) 29 (28.7%) 2.10 (1.12–3.95) 0.01
MADH4 1 (1.0%) 0 (0%)
No mutation founded 4 (3.8%) 6 (5.9%) 0.85 (0.17–3.79) 0.80
  1. ACVRL1: Activin A receptor like kinase type 1. ENG: Endoglin. MADH4 (Mother against decapentaplegic homolog 4). OR: Odds ratio. CI: Confidence interval