Skip to main content

Table 2 Peak values of the main variables determined during incremental exercise

From: Exercise training alone or in combination with high-protein diet in patients with late onset Pompe disease: results of a cross over study

 

Control

Exercise

Exercise + Diet

Before

After

p-value

Before

After

p-value

Before

After

p-value

VO2 peak (ml/min/kg)

17,77 ± 6,96

15,88 ± 4,78

0,039

19,24 ± 18,39

21,57 ± 13,26

0,053

20,22 ± 7,27

22,22 ± 4,56

0,009

VO2 peak (l/min)

1,19 ± 1,43

1,16 ± 0,77

0,023

1,23 ± 1,16

1,37 ± 0,62

0,019

1,21 ± 0,56

1,38 ± 0,44

0,027

HR peak (bpm)

143 ± 18

130 ± 14

0,16

137 ± 41

143 ± 37

0,865

146,5 ± 30

148 ± 44

0,113

HR peak (% pred)

85 ± 2

70 ± 20

0,042

82 ± 25,5

80 ± 14,5

0,905

84,5 ± 5,75

90 ± 16,25

0,059

Work rate peak (watt)

55 ± 35

45 ± 40

0,375

75 ± 80

75 ± 70

0,023

62,5 ± 55

72,5 ± 55

0,093

VCO2 peak (l/min)

1,37 ± 0,89

1,31 ± 0,95

0,195

1,34 ± 1,25

1,46 ± 0,93

0,637

1,52 ± 0,60

1,64 ± 0,76

0,039

VE peak (l/min)

45,02 ± 25,14

40,59 ± 27,39

0,195

42,48 ± 45,77

41,62 ± 36,56

0,464

47,98 ± 20,42

49,62 ± 24,29

0,064

R peak

1,06 ± 0,1

1,07 ± 0,12

0,234

1,1 ± 0,12

1 ± 0,16

0,224

1,08 ± 0,21

1,13 ± 0,16

0,75

time to exhaustion (min)

14 ± 8

13 ± 4

0,142

15 ± 15

16 ± 8

0,014

13 ± 6,25

16,5 ± 4,5

0,124

  1. Data are expressed as median ± interquartile range before and after each intervention period
  2. VO2 oxygen uptake, HR heart rate, VCO2 CO2 output, VE pulmonary ventilation, R gas exchange ratio