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Table 1 OI clinical nomenclature and estimated prevalence of OI types

From: Reproductive options for families at risk of Osteogenesis Imperfecta: a review

OI clinical type Online Mendelian Inheritance in Man (OMIM) Description of severity Estimated prevalence [11, 28, 32,33,34,35]
OI 1 166,200 Non-deforming mild OI with blue sclera ~ 46–71%
OI 2 166,210 Perinatal lethal form of OI ~ 12%
OI 3 259,420 Severe, progressively deforming OI ~ 12–28%
OI 4 166,220 Common variable OI with normal sclera ~ 12–28%
OI 5 610,967 OI with progressive calcification abnormalities ~ 2–5%