Lung function in Birt-Hogg-Dubé syndrome: a retrospective analysis of 96 patients

Table 3 Multivariable robust regression analysis of the associations between clinical characteristics and baseline lung function

Variable	FEV₁ (%pred)		FVC (%pred)		FEV₁/FVC (%pred)		TLC (%pred)		RV (%pred)		RV/TLC (%)		DLco (%pred)		DLco/V_A (%pred)
	β	p	β	p	β	p	β	p	β	p	β	p	β	p	β	p
Age (yr)	0.19	0.062	0.20	0.058	−0.09	0.129	0.07	0.591	−0.30	0.320	0.22	0.007	−0.17	0.259	0.03	0.848
Gender (F)	−2.31	0.438	2.34	0.444	−0.84	0.610	7.18	0.057	19.89	0.030	6.84	0.003	−13.58	0.002	−18.50	< 0.001
Smoking (yes)	0.24	0.935	2.55	0.395	−1.95	0.226	1.63	0.654	3.75	0.669	−0.86	0.687	−8.93	0.033	−9.11	0.053
Pleurodesis
Unilateral	−5.70	0.090	−6.22	0.071	−0.19	0.918	−0.72	0.860	10.22	0.301	4.38	0.083	2.73	0.558	5.10	0.339
Bilateral	−13.40	0.003	−20.74	< 0.001	5.52	0.024	−4.26	0.432	25.51	0.055	11.07	0.001	−9.51	0.141	4.21	0.541

FEV₁ forced expiratory volume in one second, FVC forced vital capacity, TLC total lung capacity, RV residual volume, DLco carbon monoxide transfer factor, DLco/V_A carbon monoxide transfer coefficient, yr year, F female, %pred percentage of predicted value, β partial regression coefficient. Robust linear regression model

ISSN: 1750-1172