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Fig. 3 | Orphanet Journal of Rare Diseases

Fig. 3

From: Reliability of optic disc edema area in estimating the severity of papilledema in patients with POEMS syndrome

Fig. 3

Fundus photography showing ODE improvement of an individual POEMS syndrome patient through treatment. Male, 42y, ODE was significant before treatment, with grade 2 in right eye (a) and grade 1 in left eye (b). A circumferential translucent grey area around optic disc was seen in right eye, while a c-shaped semi-opaque grey area wrapping the optic disc from temporal and upper sides was seen in left eye. All major vessels in both eyes were clear and distinct. Serum VEGF was 5922 pg/mL before treatment. After 10-month treatment, ODE was completely recovered in both eyes (c right eye, d left eye). Serum VEGF was 1547 pg/mL. ODE area of both eyes decreased markedly after treatment

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