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Table 10 Changes in Osame motor disability score (OMDS) in patients with HAM/TSP who had been observed for four years (n = 148)

From: Real-world clinical course of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) in Japan

 

Baselinea

2nd-year pointa

3rd-year pointa

4th-year pointa

5th-year pointa

∆OMDS per four yearsb

p value c

All patients

5.80 ± 2.19

5.99 ± 2.31

6.21 ± 2.36

6.28 ± 2.34

6.37 ± 2.31

0.57

(0.42–0.73)

< 0.001

Steroid group

5.96 ± 2.27

6.15 ± 2.35

6.40 ± 2.48

6.47 ± 2.51

6.60 ± 2.49

0.64

(0.30–0.98)

< 0.001

Steroid-history group

6.56 ± 2.42

6.81 ± 2.64

7.08 ± 2.61

7.14 ± 2.54

7.22 ± 2.50

0.67

(0.32–1.01)

< 0.001

Untreated group

4.84 ± 1.44

5.00 ± 1.63

5.19 ± 1.75

5.22 ± 1.81

5.25 ± 1.70

0.41

(0.13–0.68)

0.005

Miscellaneous group

5.67 ± 2.13

5.85 ± 2.14

5.97 ± 2.08

6.09 ± 1.94

6.21 ± 1.93

0.55

(0.23–0.87)

0.002

  1. aData are expressed as mean ± standard deviation
  2. bData are expressed as point estimates and 95% confidence intervals
  3. cStatistical methods used the paired t-test (baseline vs. 5th-year point)