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Fig. 5 | Orphanet Journal of Rare Diseases

Fig. 5

From: mTOR pathway in human cardiac hypertrophy caused by LEOPARD syndrome: a different role compared with animal models?

Fig. 5

Signaling activity of Erk1/2 pathway. LS, LEOPARD syndrome; SA, sarcomere mutated HCM; C, healthy controls. P indicates phosphorylated protein, and t indicates total protein. MEK, mitogen-activated protein kinase (MAPK)/extracellular signal-regulated kinase (ERK) kinase (gene name MAP2K1 and MAP2K2); ERK, extracellular signal-regulated kinase (gene name MAPK1); GAPDH, glyceraldehyde 3-phosphate dehydrogenase (gene name GAPDH), was used as a loading control

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Orphanet Journal of Rare Diseases

ISSN: 1750-1172