Fig. 4From: mTOR pathway in human cardiac hypertrophy caused by LEOPARD syndrome: a different role compared with animal models?Signaling activity of the mTOR complex 2 pathway. LS, LEOPARD syndrome; SA, sarcomere mutated HCM; C, healthy controls. P indicates phosphorylated protein, and t indicates total protein. PI3K, phosphatidylinositol-4,5-bisphosphate 3-kinase (gene name PIK3CA, PIK3CB, PIK3CG, and PIK3CD); mTOR, mammalian target of rapamycin (gene name MTOR); Akt, protein kinase B (gene name Akt1); GAPDH, glyceraldehyde 3-phosphate dehydrogenase (gene name GAPDH), was used as a loading controlBack to article page