Table 4 Univariate Andersen-Gill models: associated factors with any pneumothorax ipsilateral recurrences in PLCH patients during the study period
From: Management and outcomes of pneumothorax in adult patients with Langerhans cell Histiocytosis
Characteristic | HR | CI 95% | P value |
|---|---|---|---|
Time fixed: measured at baseline (first pneumothorax) | |||
Age | 0.99 | (0.96; 1.02) | 0.65 |
Gender | |||
Female | 1.00 | ||
Male | 1.21 | (0.61; 2.42) | 0.59 |
Tobacco smokers | 1.00 | ||
Ex-smokers | 1.39 | (0.65; 2.98) | 0.35 |
Cannabis consumption, yes | 1.71 | (0.91; 3.2) | 0.093 |
MS LCH | 1.53 | (0.8; 2.94) | 0.20 |
TLC | 0.98 | (0.95; 1) | 0.064 |
FVC | 0.98 | (0.96; 1) | 0.020 |
FEV1 | 0.98 | (0.96; 1) | 0.041 |
FEV1/FVC | 1.01 | (0.97; 1.05) | 0.67 |
Restriction | 2.08 | (0.84; 5.14) | 0.11 |
Obstruction | 0.38 | (0.12; 1.28) | 0.12 |
Air trapping | 5.08 | (1.18; 21.8) | 0.029 |
HRCT nodular score | 1.08 | (0.98; 1.19) | 0.11 |
HRCT cystic score | 1.05 | (0.93; 1.17) | 0.43 |
Predominant: | |||
thick-walled cysts | 1.76 | (0.65; 4.77) | 0.27 |
large cysts (> 1 cm) | 0.20 | (0.03; 1.43) | 0.11 |
BRAF V600E | 0.38 | (0.17; 0.85) | 0.019 |
Time-dependent: measured during the sudy period | |||
Systemic treatment | 0.68 | (0.36; 1.28) | 0.23 |
Smoking statusa | 0.73 | (0.38; 1.41) | 0.35 |
Surgery | 1.00 | (0.54; 1.87) | 1.00 |
VATS | 2.03 | (1.00; 4.12) | 0.050 |
Resection of cysts/bullae | 1.58 | (0.78; 3.2) | 0.20 |
Chemical pleurodesis | 1.48 | (0.76; 2.88) | 0.25 |
Mechanical abrasion | 0.90 | (0.48; 1.68) | 0.75 |
Apical pleurectomy | 1.22 | (0.63; 2.36) | 0.57 |