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Table 3 Mean changes of laboratory data between start of trial, end of trial and follow up period

From: Individualized treatment with denosumab in children with osteogenesis imperfecta – follow up of a trial cohort

Parameter Number of patients Start of trial End of trial End of follow up p-value Start and end of trial p-value End of trial and end of follow up
DPD/Krea (mmol/mmol) (mean ± SD) 9 48.33 ± 17.97 58.17 ± 18.6 59.31 ± 15.84 0.1149 0.8462
Serum Ca (mmol/l) (mean ± SD) 9 2.437 ± 0.068 2.563 ± 0.134 2.446 ± 0.078 0.0198 0.0174
PTH (ng/l) (mean ± SD) 8 26.50 ± 9.8 12.63 ± 5.8 22.13 ± 6.6 0.0066 0.0195