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Table 3 Mean changes of laboratory data between start of trial, end of trial and follow up period

From: Individualized treatment with denosumab in children with osteogenesis imperfecta – follow up of a trial cohort

Parameter

Number of patients

Start of trial

End of trial

End of follow up

p-value Start and end of trial

p-value End of trial and end of follow up

DPD/Krea (mmol/mmol) (mean ± SD)

9

48.33 ± 17.97

58.17 ± 18.6

59.31 ± 15.84

0.1149

0.8462

Serum Ca (mmol/l) (mean ± SD)

9

2.437 ± 0.068

2.563 ± 0.134

2.446 ± 0.078

0.0198

0.0174

PTH (ng/l) (mean ± SD)

8

26.50 ± 9.8

12.63 ± 5.8

22.13 ± 6.6

0.0066

0.0195